💙 PART 3: HDL — Why “Good Cholesterol” Isn’t Always Good

HDL has always been called the “good cholesterol,” but here’s the truth:

✨ HDL is only good when it is functioning well.

✨ High HDL is NOT always protective.

And I’ll be honest — I was very sad to learn that with HDL, the higher number is not always better. 😢

For years we believed more HDL meant more protection, but newer research shows that isn’t always true. Some women with very high HDL actually have dysfunctional HDL.

Let’s break down what that means — in simple, clear terms.

⚠️ When HDL Becomes a Problem

Two patterns suggest HDL isn’t doing its job:

1️⃣ HDL is too high

HDL above 75–85 (especially in women) can mean HDL is no longer protective — this is often “bad HDL.” 🚫💙

2️⃣ HDL particle number (HDL-P) is low

A low HDL-P means there simply aren’t enough functioning HDL particles to protect you — even if the HDL number looks fabulous on paper. 📉

Why does this happen?

Because HDL and LDL both rise in response to inflammation, toxins, infections, and oxidative stress.Your body makes more particles to help with cleanup — but they can become overloaded and dysfunctional. 🧹🔥

🛡️ What Healthy HDL Is Supposed to Do

When HDL is working properly, it is one of your strongest cardiovascular protectors. Healthy HDL is:

• 🧯 Anti-inflammatory

• 🧹 A cholesterol “clean-up crew”

• 🛡️ Antioxidant

• 🦠 Antimicrobial

• 🚫 Anti-thrombotic

• 🫀 A stabilizer of arterial plaque

• 🔄 A transporter that removes cholesterol from arteries

  
  

Dysfunctional HDL loses all these benefits — and may even worsen inflammation.

That’s why tests like HDL-P and HDLfx matter so much.

🌿 How to Improve HDL Function (Not Just the Number)

Here’s the good news: we can make HDL function better! 🙌These therapies improve HDL quality and effectiveness:

• ⭐ Niacin — one of the best for improving HDL function

• 🐟 Omega-3 fatty acids — decrease inflammation, help HDL work better

• 🍇 Resveratrol — supports antioxidant capacity

• 🍅 Lycopene — helps protect arteries

• 🍵 Green tea extract (EGCG) — excellent for HDL

• 🍈 Extra virgin olive oil — improves HDL’s antioxidant power

• 🍎 Pomegranate — supports both HDL and plaque reduction

• 🏋️‍♀️ Exercise — boosts HDL function more than it boosts HDL number

• ⚖️ Fat loss when appropriate — reduces inflammation

• 💊 Statins — surprisingly, they do improve HDL function (even if they don’t fix LDL-P)

  
  

🌱 If You Prefer to Avoid Statins

Many women prefer non-statin approaches — and that is completely reasonable when risk is low to moderate.

A supplement blend I often recommend includes:

• 🌾 Red yeast rice + CoQ10

• 🌿 Phytosterols

• 🧄 Garlic

• 🍋 Berberine

• 🌰 Tocotrienols

  
  

This combination supports cholesterol production, absorption, inflammation, and liver metabolism.

🔑 Other Key Factors That Shape HDL Health

These are often overlooked but incredibly important:

• 🌞 Vitamin D goal: around 80

• 🩸 Triglycerides ideal: < 75

• 🦋 Thyroid function — even slightly low thyroid can make HDL dysfunctional

• 🔥 Inflammation — the #1 cause of “bad HDL”

  
  

Anything that raises inflammation can impair HDL’s ability to protect you.

💙 The Big Picture: HDL Must Be Functional

HDL is not automatically “good.”What matters is how well HDL works — not how high the number goes.

When HDL is healthy and functional, it:

• 🧹 Removes cholesterol from arteries

• 🧯 Lowers inflammation

• 🛡️ Stabilizes plaque

• 🚫 Helps prevent heart attack and stroke

• 🫀 Supports vascular healing

  
  

When HDL becomes dysfunctional, it loses these benefits — even when the HDL level looks impressive.

The wonderful news?

We can restore HDL function through:

• Reducing inflammation

• Supporting thyroid health

• Improving metabolic function

• Using targeted supplements

• Optimizing hormones (especially estrogen during midlife)

• Improving lifestyle and nutrition

  
  

This is functional and personalized cardiometabolic care at its best. 💛