GLP-1s: How They Work, What Your Body Already Does, and When I Use Them
- waymire
- 4 days ago
- 2 min read
GLP-1 medications are everywhere right now, but before jumping to prescriptions, I want women to understand one important thing:
You already make your own GLP-1. 🙌
And we can often support it naturally before turning to medication.

What Is GLP-1?
GLP-1 (glucagon-like peptide-1) is a hormone your gut releases after you eat. It helps:
🧠 Signal fullness
🍽️ Slow stomach emptying
💙 Improve insulin response
🔥 Keep blood sugars stable
When GLP-1 works well, appetite is calmer and metabolism runs more smoothly.
Why It Matters in Midlife
Stress, poor sleep, perimenopause, blood sugar swings, and ultra-processed foods all decrease our natural GLP-1 response. The good news? Supplements, fiber, protein, movement, and gut health all help support your own GLP-1 production naturally. 🌿
What About GLP-1 Medications?
Medications like semaglutide mimic your natural GLP-1 but in higher, steadier amounts. They can be incredibly helpful for women with insulin resistance, prediabetes, or long-standing weight struggles.
I do prescribe GLP-1s, but in a thoughtful, individualized way.
My Microdosed Sublingual GLP-1 Option 💊
Through my amazing compounding pharmacist, I offer a daily, microdosed sublingual GLP-1. Women love it because it’s gentle, adjustable, and taken under the tongue.
But…
GLP-1s Are Not My First Choice
Most women do beautifully with a more foundational approach first. My favorites:
📱 Lose It! app to increase awareness around calories in/calories out
🏋️♀️ Resistance training
🚶♀️ Brisk walks after meals
🍗 Protein + 🥗 fiber at meals
💊 Low-dose naltrexone when needed
These support metabolism at the root, not just the appetite.
When I Do Use GLP-1s
GLP-1s become helpful when a woman has:
Truly tried lifestyle changes
Plateaued despite great effort
Metabolic complications
Or feels like nothing is working
And when we use them, they’re part of a full plan, not the whole plan.
Bottom Line
GLP-1s are a tool, not a magic fix.And they work best when they support a foundation of lifestyle changes—not replace them. ✨
If you’re curious whether a GLP-1 could help you, we can talk through all the options at your visit—no pressure, always personalized.